5-HT<sub>2A</sub> receptors in layer 5 pyramidal neurons mediate the neuroplastic but not the hallucinogenic effects of psilocybin
https://www.nature.com/articles/s41593-026-02490-y
https://www.nature.com/articles/s41593-026-02490-y
Nature
5-HT2A receptors in layer 5 pyramidal neurons mediate the neuroplastic but not the hallucinogenic effects of psilocybin
Nature Neuroscience - Psilocybin promotes and stabilizes new connections between neurons in the mouse cerebral cortex, especially after stress. Baker et al. show that 5-HT2A receptor signaling in...
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| First 24 hours | ||
|---|---|---|
| Hour | Growth | Total |
| 18:46+1h | +157 | 157 |
| 19:46+2h | +29 | 186 |
| 20:46+3h | +28 | 214 |
| 21:46+4h | +29 | 243 |
| 22:46+5h | +29 | 272 |
| 23:46+6h | +28 | 300 |
| 00:46+7h | +29 | 329 |
| 01:46+8h | +28 | 357 |
| 02:46+9h | +29 | 386 |
| 03:46+10h | +29 | 415 |
| 04:46+11h | +28 | 443 |
| 05:46+12h | +29 | 472 |
| 06:46+13h | +16 | 488 |
| 07:46+14h | +17 | 505 |
| 08:46+15h | +16 | 521 |
| 09:46+16h | +17 | 538 |
| 10:46+17h | +16 | 554 |
| 11:46+18h | +17 | 571 |
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| 14:46+21h | +17 | 620 |
| 15:46+22h | +16 | 636 |
| 16:46+23h | +17 | 653 |
| 17:46+24h | +16 | 669 |
| By day | ||
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| Date | Growth | Total |
| Thu, Oct 15 | +669 | 669 |
| Fri, Oct 16 | +79 | 748 |
| Sat, Oct 17 | +2 | 750 |
| Sun, Oct 18 | +1 | 751 |
| Mon, Oct 19 | +2 | 753 |
| Tue, Oct 20 | +1 | 754 |
| Wed, Oct 21 | +2 | 756 |
| Thu, Oct 22 | +1 | 757 |
| Fri, Oct 23 | +2 | 759 |
| Sat, Oct 24 | +1 | 760 |
| Sun, Oct 25 | +2 | 762 |
| Mon, Oct 26 | +1 | 763 |
| Tue, Oct 27 | +2 | 765 |
| Wed, Oct 28 | +2 | 767 |
| Thu, Oct 29 | +1 | 768 |